Seizing an opportunity for the endocannabinoid system.

Study the Effect of Endocannabinoid System on Rat Behavior in Elevated Plus-Maze

Introduction: Previous studies have shown that cannabinoidergic system is involved in anxiety. However, there are controversial reports in the experimental studies. The aim of this study is to evaluate the effect of pharmacological stimulation or blocking of CB1 receptors and inhibition of endocannabinoid degradation in anxiety like behavior in elevated plus-maze (EPM) test in rat. The EPM is o...

Commentary: Comment on the Effect of Endocannabinoid System on Rat Behavior

I read the recently published article in Vol 6 (3) of Basic and Clinical Neuroscience entitled “Study the Effect of Endocannabinoid System on Rat Behavior in Elevated Plus- Maze” by Komaki et al. (2015). In this valuable article, the authors uncovered the effects of AM251 as a CB1 receptor antagonist on anxiety-like behaviors of rats using elevated plus-maze

P 117: Endocannabinoid System as a Novel Therapeutic Target in Epilepsy

Endocannabinoid (ECB) system plays a vital role in responses to stress. Moreover, ECB and its receptors cause anti-inflammatory, anti-oxidative and neuroprotective effects by modulating neuronal, glial and endothelial cell functions. A number of studies have demonstrated ECB system notably defects in neurotraumatic and neurodegenerative diseases like epilepsy, TBI, Alzheimer’s disease and...

Seizing the Digitalization Opportunity

میزان تأثیر سه روش تمرینی وامانده ساز هوازی، بی‌هوازی و مقاومتی بر سیستم اندوکانابینوئید در مردان جوان: یک کارآزمایی بالینی

Background and Objectives: One of the most common challenges for human physiological system is exercise. Therefore, the aim of this study was determining the effect of different types of exercise on endocannabinoid system agents such as anandamide (AEA) and 2-arsidonyl glycerol (2-AG). Materials and Methods: In this clinical trial study, 32 young men (19-25 years old) volunteered from among st...